Empower patients with episodes of frequent seizures to act fast

The best time to treat a seizure is as early as possible

Empower patients with episodes of frequent seizures to act fast

A single line of seizure defense with current ASMs may not be enough

You work hard to optimize your patients’ antiseizure medications (ASMs)

However, patients who appear well controlled on ASMs may not be seizure free.

  • Up to 40% experience breakthrough seizures despite ASM therapy1
  • Episodes of frequent seizures occurred in 71% of patients experiencing >4 seizures per year2
  • Other factors associated with episodes of frequent seizures include:
    • A history of prolonged seizures or status epilepticus3-5
    • A history of injuries sustained during seizure episodes2
    • A history of multiple seizure types5
    • A greater number of current antiseizure medications5
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The unpredictable nature of seizures has a profound impact6

  • In a survey of 259 adults experiencing or managing episodes of frequent seizures6:
    • 75% reported living in fear that they will have a seizure at any time
    • 80% reported a significant emotional burden
  • People with epilepsy desire independence but are often afraid to leave the home7

Adult patients may not always report their seizures for fear of losing their independence,8 making it hard to optimize treatment

Prepare patients with episodes of frequent seizures with the right on-hand treatment

3x increased risk of death

Untreated seizures can lead to a greater risk of permanent consequences

  • 3x significantly increased risk of death in patients experiencing episodes of frequent seizures9
  • Neuronal damage from recurrent seizures can have behavioral and cognitive consequences10
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The best time to treat an episode of frequent seizures is as early as possible

  • The longer a seizure is left untreated, the more difficult it may be to treat11,12
  • Benzodiazepines are most effective when used early after a seizure starts, due to changes at synapses that degrade GABA signaling over time11,12

Your patients want to act, not wait

When episodes of frequent seizures occur, patients don’t want to wait to be “rescued.” Having an immediate-use seizure medication on hand allows patients and care partners to act quickly.

Seizure rescue medication or immediate-use seizure medication?
The term “seizure rescue medication” reinforces the notion that patients need to be saved. Instead, “immediate-use seizure medication” emphasizes how quickly the medication may be used to empower patients to treat sooner.

Talk with your patients about the importance of having an immediate-use seizure medication

Along with an ASM, a nasal option that can be used at any time during a seizure episode could provide more comprehensive management for more of your patients at risk.13,14

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Ensure patients are prepared to act quickly with an immediate-use seizure medication

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